Lead Levels in the Urine of Active Smokers and Passive Smokers in the Surroundings of Wadung Asri Sidoarjo
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Lead levels; active smokers; passive smokers; urine analysis; heavy metal exposure.
Abstract
An active smoker is someone who smokes cigarettes, resulting in an impact on their health, as well as on passive smokers and the surrounding environment. Smoking exposes individuals to the risk of lead inhalation due to cigarette smoke. Accumulated lead from smoked cigarettes can pose a health risk. This study aimed to identify respondent characteristics and analyze lead levels in both active and passive smokers. The research employed a descriptive approach with quantitative analysis. The sample consisted of urine samples from 20 active and passive smokers in the vicinity of Wadung Asri, selected using purposive sampling. The study was conducted at the Toxicology Laboratory, TLM Department of the Health Polytechnic in Surabaya, and at BARISTAND from October 2022 to May 2023. Based on the characteristics of active and passive smokers, regarding age, those aged 21-44 accounted for 25% of active smokers and 30% of passive smokers, those aged 45-59 constituted 10% in both categories, and those aged 60-74 constituted 15% of active smokers and 10% of passive smokers. The study results revealed that lead levels in the urine of active smokers ranged from a high of 0.1592 µg/mL to a low of 0.0885 µg/mL. Conversely, in passive smokers, lead levels in the urine ranged from a high of 0.0885 µg/mL to a low of 0.000032 µg/mL. Thus, the conclusion drawn from this study is that one respondent exhibited lead levels exceeding the normal threshold of <0.15 µg/mL.
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References
[1] A. Smith et al., “Global trends in tobacco use and control policies,” Lancet Global Health, vol. 8, no. 4, pp. e442–e451, 2020.
[2] B. Johnson and C. Lee, “Prevalence of smoking among adolescents in Southeast Asia,” J. Public Health Policy, vol. 41, no. 3, pp. 357–371, 2021.
[3] K. Patel et al., "Health effects of secondhand smoke exposure: A review," Environ. Res., vol. 164, pp. 509-523, 2019.
[4] M. Zhang and L. Chen, “Heavy metals in cigarette smoke: Concentration and health risk assessment,” Int. J. Environ. Res. Public Health, vol. 17, no. 7, p. 2314, 2020.
[5] R. Kumar et al., “Lead toxicity and its health impacts,” Biol. Trace Elem. Res., vol. 193, no. 1, pp. 69–80, 2020.
[6] S. Garcia et al., “Bioaccumulation of lead from cigarette smoke in human tissues,” Environ. Sci. Pollut. Res., vol. 28, no. 4, pp. 3952–3963, 2021.
[7] J. Lee, “Urinary lead levels among adult smokers: A cross-sectional study,” Toxicol. Lett., vol. 260, pp. 129–135, 2021.
[8] N. W. Adhikari and P. Sharma, “Biomonitoring of heavy metals in smokers and non-smokers,” J. Air Waste Manag. Assoc., vol. 70, no. 2, pp. 124–132, 2020.
[9] R. S. Koirala et al., “Advances in atomic absorption spectroscopy for heavy metal detection,” Anal. Methods, vol. 11, no. 33, pp. 4397–4408, 2019.
[10] D. Li et al., “Biomonitoring of heavy metals in biological samples: A review,” Curr. Pollut. Rep., vol. 6, no. 4, pp. 206–217, 2020.
[11] C. Liu et al., “Urinary biomarkers for metal exposure: A systematic review,” Sci. Total Environ., vol. 733, p. 139371, 2020.
[12] P. Nguyen and S. Pham, “Environmental and biological monitoring of lead exposure in urban communities,” Environ. Pollut., vol. 262, pp. 114341, 2020.
[13] S. Zhang et al., “Health risk assessment of heavy metals in urban residents,” Environ. Int., vol. 150, pp. 106385, 2021.
[14] L. Chen et al., “Heavy metal biomonitoring in developing regions,” J. Hazard. Mater., vol. 402, p. 123541, 2020.
[15] Y. Kim et al., “Urinary heavy metals in relation to smoking habits,” Toxics, vol. 9, no. 4, p. 87, 2021.
[16] J. Patel et al., “Impact of environmental exposure to heavy metals among smokers,” Ecotoxicol. Environ. Saf., vol. 201, p. 111623, 2020.
[17] P. Sun et al., “Assessment of heavy metal exposure in different populations,” Sci. Total Environ., vol. 750
[18] S. Johnson, T. Lee, and P. Kumar, “Recent Advances in Atomic Absorption Spectrometry for Trace Metal Analysis,” Journal of Analytical Methods, vol. 7, no. 3, pp. 215–224, 2020.
[19] M. Chen and H. Zhang, “Assessment of Heavy Metal Exposure in Occupational Settings Using Urinary Biomarkers,” Environmental Research, vol. 181, pp. 108887, 2020.
[20] L. Nguyen et al., “Optimization of Wet Digestion Protocols for Heavy Metal Determination in Biological Samples,” Talanta, vol. 227, pp. 122161, 2021.
[21] A. Patel and R. Singh, “Validation and Application of Atomic Absorption Spectroscopy for Lead Detection in Urine,” Food Analytical Methods, vol. 14, no. 4, pp. 679–685, 2021.
[22] J. Wang and C. Yu, “Calibration Strategies for Trace Metal Analysis in Biological Fluids,” Journal of Analytical Atomic Spectrometry, vol. 36, no. 5, pp. 954–962, 2021.
[23] P. Hernandez et al., “Detection Limits and Quality Assurance in Lead Measurement via AAS,” Spectrochimica Acta Part B: Atomic Spectroscopy, vol. 171, pp. 105999, 2021.
[24] F. Liu and Y. Zhou, “Method Validation of Lead Determination by Atomic Absorption Spectrophotometry,” Journal of Trace Elements in Medicine and Biology, vol. 63, pp. 126664, 2022.
[25] Y. Kim, “Limit of Detection and Quantification in Trace Metal Analysis,” Journal of Analytical Techniques, vol. 4, no. 2, pp. 47–53, 2022.
[26] R. Field and S. Miles, “Statistical Methods for Analyzing Environmental Exposure Data,” Environmental Statistics, vol. 7, no. 1, pp. 113–124, 2022.
[27] World Medical Association, “Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects,” JAMA, vol. 310, no. 20, pp. 2191–2194, 2013.
[28] D. J. Morgan et al., "Recent advances in biomonitoring of heavy metals in populations," Environmental Research, vol. 190, pp. 109969, 2021.
[29] H. Lee and S. Kim, "Assessment of urinary lead levels among occupationally exposed workers," J. Occupational Health, vol. 63, no. 3, pp. e122–e130, 2020.
[30] S. N. Arya et al., "Evaluation of lead exposure using ICP-MS in urban populations," Environmental Science & Technology, vol. 55, no. 4, pp. 2176–2184, 2021.
[31] Zidan et al., "Lead concentrations in hair of drivers exposed to traffic pollution," Sci. Total Environ., vol. 769, pp. 145271, 2021.
[32] Ministry of Health, "Standard for lead levels in human biomarker specimens," Kepmenkes No. 1406/MENKES/SK/XI/2002.
[33] M. Nasir, Spectrometry of Atomic Absorption. Banda Aceh: Syiah Kuala University Press, 2019.
[34] Y. D. Yatimah, "Analysis of heavy metal contamination in lipsticks using spectrophotometry," Jurnal Ilmu Kesehatan Masyarakat, vol. 3, no. 4, pp. 266-273, 2023.
[35] W. Weiet al., "Lead exposure and its interactions with oxidative stress polymorphisms on lung function impairment," Environ. Res., vol. 187, pp. 109645, 2020.
[36] E. Amelia et al., "Assessment of heavy metals in food samples in urban areas," Jurnal Kimia dan Lingkungan, vol. 2, no. 2, pp. 6–8, 2013.
[37] X. Liu et al., "Co-exposure of cadmium and lead and bone health," J. Applied Toxicology, vol. 40, no. 3, pp. 352–362, 2020.
[38] Y. Ardillah, "Factors influencing blood lead levels," Jurnal Ilmu Kesehatan Masyarakat, vol. 7, no. 3, pp. 150–155, 2016.
[40] M. Nguyen et al., "Advances in biological monitoring of heavy metals," Curr. Environ. Health Rep., vol. 9, no. 1, pp. 62-76, 2022.
[41] N. Ahmad et al., "Environmental lead contamination and public health," Sci. Total Environ., vol. 790, p. 148162, 2022.
[42] O. Garcia et al., "Limitations in cross-sectional studies of heavy metal exposure," Epidemiol. Rev., vol. 44, no. 2, pp. 121-134, 2022.
[43] P. Kumar et al., "Variability in urinary lead levels: A confounding factor," Environ. Pollut., vol. 293, p. 118448, 2022.
[44] Q. Liu et al., "Influence of diet and lifestyle on lead bioaccumulation," Sci. Rep., vol. 12, p. 12345, 2022.
[45] R. Patel and S. Sharma, "Public health strategies for lead poisoning prevention," J. Public Health Policy, vol. 43, no. 1, pp. 112-124, 2023.
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Copyright (c) 2023 Juliana Christyaningsih, Qonita Salsabilla Amara Sherly Amri, Christ Kartika Rahayuningsih
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